发明名称 New antitumour platinum(II) complexes and process for their preparation
摘要 The present invention relates to platinum complexes having antitumour activity represented by the general formula (I): <IMAGE> in which A is chosen from ammine and primary alkyl- and cycloalkylamine monodentate ligands having 1-3 carbon atoms, such as methyl-, ethyl-, n-propyl-, isopropyl- and cyclopropylamines or else the two amine groups can be combined in a diamine <IMAGE> diaminocyclohexane and 2-hydroxy-1,3-diaminopropane, and X is either a vinylene group (-CH=CH-) or an ethylene group (-CH2-CH2-) when it is bonded to two sulphur atoms in the cyclic form or represents two methyl groups bonded separately to each sulphur atom.
申请公布号 FR2678623(A1) 申请公布日期 1993.01.08
申请号 FR19910013278 申请日期 1991.10.28
申请人 KOREA INSTITUTE SCIENCE TECHNOLO 发明人 SOHN YOUN SOO;KIM KWAN MOOK
分类号 A61K31/28;A61K31/282;A61P35/00;C07F15/00 主分类号 A61K31/28
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