发明名称 MONOCLONAL ANTIBODY TO LYMPHOCYTE-ASSOCIATED CELL SURFACE PROTEIN
摘要 A hybridoma cell line produced by the fusion of NS-1 myeloma cells with spleen cells obtained from mice immunized with Leukocyte Adhesion Molecule-1 (LAM-1) cDNA transfected cells. The cell line produces a monoclonal antibody reactive with human, monkey, cow, rabbit, sheep, dog, ca t, pig and goat LAM-1. The monoclonal antibody produced by the cell line, anti-LAM1-3, may be clinically useful in blocking leukocyte entry into sites of inflammation or tissue injury.
申请公布号 CA2336561(A1) 申请公布日期 1993.01.07
申请号 CA19922336561 申请日期 1992.06.24
申请人 DANA-FARBER CANCER INSTITUTE 发明人 TEDDER, THOMAS F.;SPERTINI, OLIVIER G.
分类号 A61K39/395;C07K16/28;C12N5/12;C12N5/18;C12P21/08;G01N33/532;G01N33/577;(IPC1-7):C12N5/12 主分类号 A61K39/395
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