发明名称 |
ATTENUATED REVERTANT SEROTYPE 1 MAREK'S DISEASE VACCINE |
摘要 |
A Marek's disease vaccine comprising an attenuated revertant virus derived as a clone of Md11/75/R2 or an antigenic component of the virus is characterized by a markedly reduced pathogenicity compared to the parent virus, without a comparable loss in immunogenicity. Attenuated revertants of the invention are exemplified by Md11/75/R2/23 and Md11/75/R2/29. These viruses or immunogenic components thereof can be formulated into monovalent and polyvalent vaccines. |
申请公布号 |
WO9300112(A1) |
申请公布日期 |
1993.01.07 |
申请号 |
WO1992US05249 |
申请日期 |
1992.06.26 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE |
发明人 |
WITTER, RICHARD, L. |
分类号 |
A61K39/255;A61K39/00;A61P31/12;C07K14/055 |
主分类号 |
A61K39/255 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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