发明名称 |
BIOMATERIALS BASED ON MIXTURES OF COLLAGEN, CHITOSAN AND GLYCOSAMINOGLYCANS, METHOD FOR PREPARING THEM AND THEIR USE IN HUMAN MEDICINE |
摘要 |
<p>This biomaterial comprises at least a compound consisting of an association of collagen, chitosan acetylated to a degree of acetylation between about 10 and about 40% and of glycosaminoglycans. It has its application in orthopedics and plastic surgery and for making extracellular matrices for regeneration of nerve cells and bones as well as biocompatible envelopes. A particular application is the making of artificial skin consisting of a dermal layer of the velvet type obtained from biomaterials such as those described above. The process of obtaining this dermal layer consists in adding a collagen solution of the chitosan, then in adding to the collagen-chitosan a mixture of chondroitins 4- and 6-sulfate.</p> |
申请公布号 |
GR3002084(T3) |
申请公布日期 |
1992.12.30 |
申请号 |
GR19910400755T |
申请日期 |
1991.06.06 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) |
发明人 |
COLLOMBEL, CHRISTIAN;DAMOUR, ODILE;GAGNIEU, CHRISTIAN;POINSIGNON, FREDERIQUE;ECHINARD, CHRISTIAN;MARICHY, JACQUES |
分类号 |
A61L27/00;A61L27/26;A61L27/34;C08L89/06;C12N5/00;(IPC1-7):A61L31/00 |
主分类号 |
A61L27/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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