发明名称 |
Heterocyclic compounds, their production and use as angiotensin II antagonists. |
摘要 |
<p>Compounds shown by the above formula or salt thereof show a strong angiotensin II antagonistic activity and hypotensive action and CNS activity, and are useful as therapeutic agents of circulatory diseases such as hypertensive diseases and heart diseases (e.g. hypercardia, heart failure, cardiac infarction), strokes, cerebral apoplexy, nephritis, atherosclerosis, Alzheimer's disease, senile dementia, etc. <CHEM> h</p> |
申请公布号 |
EP0520423(A2) |
申请公布日期 |
1992.12.30 |
申请号 |
EP19920110668 |
申请日期 |
1992.06.25 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
NAKA, TAKEHIKO;INADA, YOSHIYUKI |
分类号 |
A61K31/415;A61K31/41;A61K31/42;A61K31/4245;A61K31/433;A61K31/435;A61K31/4365;A61K31/495;A61K31/505;A61K31/513;A61K31/517;A61K31/535;A61P9/00;A61P9/10;A61P9/12;A61P25/28;A61P43/00;B29D22/00;B32B27/42;C07D285/08;C07D403/10;C07D413/10;C07D417/10;C07D419/10;C07D471/04;C07D487/04;C07D495/04;C07D519/00 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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