发明名称 NOVEL BIOLOGICALLY ACTIVE PEPTIDE COMPOSITIONS AND USES THEREFOR
摘要 A biologically active peptide which includes the following structure: R1-R1-R1-R3-R5-R1-R1-R1-R1-R1-R2-R2-R1-R1R3- R1-R4-R1-R3-R4-R1-R1. R1 is a hydrophobic amino acid, R2 is a basic hydrophilic amino acid, and R3 is a neutral hydrophilic amino acid, R4 is a hydrophobic or basic hydrophilic amino acid, and R5 is a hydrophobic, basic hydrophilic, or neutral hydrophilic amino acid. Examples of such peptides include the following: (SEQ ID NO:1)-NH2; (SEQ ID NO:2)-NH2; (SEQ ID NO:3)-NH2; (SEQ ID NO:4)-NH2; (SEQ ID NO:5)-NH2; (SEQ ID NO:6)-NH2; (SEQ ID NO:7)-NH2; and (SEQ ID NO:8). The peptides may be employed in pharmaceutical compositions.
申请公布号 AU2154692(A) 申请公布日期 1992.12.30
申请号 AU19920021546 申请日期 1992.05.08
申请人 THE CHILDREN'S HOSPITAL OF PHILADELPHIA 发明人 MICHAEL A ZASLOFF;W. LEE MALOY;U. PRASAD KARI
分类号 A61K38/00;A61P31/04;A61P31/10;A61P31/12;A61P35/00;C07K14/46 主分类号 A61K38/00
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