| 摘要 |
PCT No. PCT/JP89/00288 Sec. 371 Date Dec. 29, 1989 Sec. 102(e) Date Dec. 29, 1989 PCT Filed Mar. 17, 1989 PCT Pub. No. WO89/08645 PCT Pub. Date Sep. 21, 1989.A process for preparing pyridine-2,3-dicarboxylic acid compounds of the following formula, which comprises preparing alpha -halo-oxalacetic acid diesters by reacting oxalacetic acid diester alkali metallic salts with an acid and a halogenating agent or by reacting oxalic acid diesters with halo-acetic acid esters, and then reacting the obtained alpha -halo-oxalacetic acid diesters with 2-propenal compounds and ammonia. <IMAGE> wherein R1 and R2 are, identical or different, a lower alkyl group, and R3 is a hydrogen atom or a lower alkyl group. The pyridine-2,3-dicarboxylic acid componds obtained by the process of the ivention are useful as an intermediate for manufacturing agricultural chemicals and pharmaceuticals.
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