Tablet extraction and analysis system and method

摘要

A tablet extractor includes a housing which defines a cylindrical chamber having a bottom wall and a side wall. A relief is formed in a sector of the chamber side wall which creates a relatively sharp knife edge. An impeller rotatably mounted in the housing includes a rigid finger which extends along the chamber, that finger having a leading face which extends generally radially and a radially outer surface which follows closely the unrelieved portions of the chamber side wall. There is an opening in the bottom wall of the chamber and a second opening in the chamber side wall. When the impeller is rotated so that the finger rotates toward the knife edge, the extractor can recirculate liquid and a tablet and parts thereof entrained in the liquid through the chamber for mixing and can position the tablet while in the chamber for impaction against the knife edge to pulverize the tablet. A complete automated extraction and analysis workstation incorporating the tablet extractor is also disclosed.