PROCESS FOR PRODUCING TERT BUTYLPHENYL-1-CYCLIC AMINO-4-HYDROXYBUTANE DERIVQTIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS

摘要

PCT No. PCT/FR91/00811 Sec. 371 Date Feb. 8, 1993 Sec. 102(e) Date Feb. 8, 1993 PCT Filed Oct. 17, 1991 PCT Pub. No. WO92/06977 PCT Pub. Date Apr. 30, 1992. (I) The present invention concerns (4-substituted phenyl)4-oxy 1-aminobutane of the general formula (I) in which X is a nitrogen atom or >CH-CH, and R is a cyclic substituent chosen from the group comprising a) a xanthic substituent, b) a benzimidazolic substituent, as well as salts and optic isomers of the compounds of formula (I). The invention also concerns processes for obtaining the compounds of formula (I) and pharmaceutical compositions containing, as antihistamine ingredient, at least one compound of formula (I) or one of its salts with a mineral or organic acid.