发明名称 |
FOERFARANDE FOER FRAMSTAELLNING AV DIACETYLRHEIN |
摘要 |
The invention relates to a process for the preparation of diacetylrhein in pharmaceutically acceptable purity with a remainder of undesired aloe emodin derivatives of less than 20 ppm in total. The process consists in subjecting aloe emodin components of the diacetylrhein to a liquid-liquid partition followed by crystallisation and drying the product under particularly mild conditions. The invention also relates to the diacetylrhein which can be obtained by this process, and to a pharmaceutical composition containing this compound. |
申请公布号 |
FI922930(A) |
申请公布日期 |
1992.12.26 |
申请号 |
FI19920002930 |
申请日期 |
1992.06.24 |
申请人 |
MADAUS AKTIENGESELLSCHAFT |
发明人 |
CARCASONA, ALFONS;GRIMMINGER, WOLF;HIETALA, PENTTI;WITTHOHN, KLAUS;ZAESKE, HELGA |
分类号 |
A61K31/22;A01N37/10;A61K31/19;A61K31/192;A61K31/222;A61K31/235;A61K36/18;A61P19/02;A61P25/04;A61P29/00;C07C67/48;C07C67/52;C07C67/58;C07C69/00;C07C69/157;C07C69/16;C07C69/95 |
主分类号 |
A61K31/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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