| 摘要 |
Stabilised growth promoting formulation comprises a growth promoting hormone (I) and a stabiliser which decreases the formation of insoluble and improves preservation of soluble bioactivity of (I) in aq. media. The stabiliser comprises 1 or more of (a) a polyol from non-reducing sugars, sugar alcohols, sugar acids, lactose, pentaerythritol, water-soluble dextrans and Ficoll; (b) an amino acid from glycine, sarcosine, lysine, serine, arginine, betaine, N,N-dimethylglycin, aspartic acid, glutamic acid and their salts; (c) a polymer of an amino acid having a charged side gp. at physiological pH; and (d) a choline deriv. from choline chloride, -dihydrogen citrate, -bitartrate, -bicarbonate, -ascorbate, -borate, -gluconate or -phosphate and dicholine sulphate, dicholine mucate and tridoline citrate. (I) may be an ovine, porcine, equine, avian, bovine or human growth promoting hormone.
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