| 摘要 |
<p>A process for producing a hexahydropyridazine-1,2-dicarboxylic acid derivative represented by general formula (3) industrially in a good yield; wherein R represents alkoxy or aryl, which comprises reacting a hydrazinedicarboxylic acid derivative represented by the general formula (1): ROC-NH-HN-COR, wherein R is as defined above, with a dihalogenobutane represented by the general formula (2): X-CH2CH2CH2CH2-X, wherein X represents chlorine or bromine, in the presence of a base selected between alkali metal carbonate and hydroxide. <CHEM></p> |
