摘要 |
Compounds of structure (I), in which R is C1-8alkyl, C1-8alkyl(phenyl), C2-8alkenyl(phenyl)p, C2-8alkynyl(phenyl)p, C3-8cycloalkyl or C1-8alkylC3-8cycloalkyl; p is 0 to 2; n is 0 to 6; A is a bond, -CH=CH-, -C=C-, oxygen, sulphur or NR<1>; R<1> is hydrogen, C1-8alkyl or phenylC1-4alkyl; m is 0 to 3; and Ar is aryl or heteroaryl, each of which may be optionally substituted, and their pharmaceutically acceptable salts as calcium channel antagonists. Novel compounds of structure (I), processes for preparing them and pharmaceutical compositions containing them are also described. |