发明名称 COMPOUNDS
摘要 Compounds of structure (I), in which R is C1-8alkyl, C1-8alkyl(phenyl), C2-8alkenyl(phenyl)p, C2-8alkynyl(phenyl)p, C3-8cycloalkyl or C1-8alkylC3-8cycloalkyl; p is 0 to 2; n is 0 to 6; A is a bond, -CH=CH-, -C=C-, oxygen, sulphur or NR<1>; R<1> is hydrogen, C1-8alkyl or phenylC1-4alkyl; m is 0 to 3; and Ar is aryl or heteroaryl, each of which may be optionally substituted, and their pharmaceutically acceptable salts as calcium channel antagonists. Novel compounds of structure (I), processes for preparing them and pharmaceutical compositions containing them are also described.
申请公布号 WO9222527(A2) 申请公布日期 1992.12.23
申请号 WO1992GB01088 申请日期 1992.06.17
申请人 SMITHKLINE BEECHAM PLC 发明人 BROWN, THOMAS, HENRY;COOPER, DAVID, GWYNN;KING, RONALD, JOSEPH
分类号 A61K31/40;A61K31/4025;A61P25/08;A61P25/28;A61P25/30;C07D207/08;C07D207/09;C07D405/12 主分类号 A61K31/40
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