| 发明名称 |
Insulin analogs. |
| 摘要 |
Analogs of human insulin containing an Asp residue at position 10 of the B chain, having a truncated carboxyl terminus of the B chain and, optionally, having modifications at other positions display modified physico-chemical and pharmacokinetic properties. These analogs are useful in the treatment of hyperglycemia.
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| 申请公布号 |
EP0519750(A2) |
申请公布日期 |
1992.12.23 |
| 申请号 |
EP19920305678 |
申请日期 |
1992.06.19 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
BREMS, DAVID NETTLESHIP;CHANCE, RONALD EUGENE;FRANK, BRUCE HILL |
| 分类号 |
A61K38/28;A61K38/00;A61P3/08;A61P3/10;C07K14/575;C07K14/62;C12P21/02;C12P21/04 |
主分类号 |
A61K38/28 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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