发明名称 HETEROCYCLIC COMPOUNDS WITH RENIN-INHIBITING PROPERTIES, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF
摘要 HOE 91/F 187 of the disclosure Heterocyclic compounds of the formula (I) ( I ) in which the radicals have the following meanings: R1 for example propyl and isobutyl R2 for example phenyl or pyridyl R3 for example hydrogen, R4 for example cyclohexylmethyl R5 for example hydrogen or hydroxyl R6 a radical of the formula (II) (CH2)s-CHR7-z (II) where R7 is for example hydrogen, z is a 5- to 7-membered heterocyclic ring and s is 0, 1, 2, 3 or 4; are potent renin-inhibiting compounds.
申请公布号 CA2071743(A1) 申请公布日期 1992.12.22
申请号 CA19922071743 申请日期 1992.06.19
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 HEITSCH, HOLGER;HENNING, RAINER;URBACH, HANSJOERG;RUPPERT, DIETER;LINZ, WOLFGANG
分类号 A61K31/495;A61P9/12;A61P43/00;C07D241/10;C07D249/08;C07D401/04;C07D487/04;C07D519/00;(IPC1-7):C07D487/04;A61K31/535;A61K31/54 主分类号 A61K31/495
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