摘要 |
The preparation and use of polynucleotides and polypeptides corresponding to a novel gene expressed in fetal intestinal endoderm cells and the corresponding gene product, respectively, are disclosed. Expression of the gene, designated the intestinal oncofetal gene, is associated with neoplastic transformation in non-fetal intestinal cells other than adult crypt cells. Clone OCI-5 was deposited at the American Type Culture Collection, 12301 Parklawn Drive, Rocksville, Maryland 20852, U.S.A., on Aug. 18, 1988, and granted accession No. 40481.
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