摘要 |
PCT No. PCT/EP89/01087 Sec. 371 Date Apr. 23, 1991 Sec. 102(e) Date Apr. 23, 1991 PCT Filed Sep. 19, 1989 PCT Pub. No. WO90/03179 PCT Pub. Date Apr. 5, 1990.It is known to produce effervescent tablets incorporating salicyl acid analgetics gained synthetically, and, is required, vitamin adjuvants. In order to avoid the disadvantages of synthetically manufactured salicyl acid in such effervescent tablets, namely the irritation of the gastric mucosas and the inhibition of thrombocyte aggregation, and simultaneously to bring about new fields of use for effervescent tablets, an effervescent tablet is suggested which has, as an analgesic agent forming salicyclic acid, a water-soluble plant extract of the salicis extract type (willow bark extract) with a high active substance content. Thus, a galenically appropriate administration form of these generally extremely hygroscopic extracts is obtained. In the effervescent tablet, high active substance quantities can be resorbed rapidly, the salicyl acid forming the final active substance only being formed in the liver.
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申请人 |
STEPHAN, DIETER;HONERLAGEN, HANS;MITSCHKA, JOCHEN;STEPHAN, GUENTER |
发明人 |
STEPHAN, DIETER;HONERLAGEN, HANS;MITSCHKA, JOCHEN;STEPHAN, GUENTER |