发明名称 VECTEUR PARTICULAIRE A TROPISME SELECTIF, PROCEDE DE PREPARATION ET COMPOSITION PHARMACEUTIQUE.
摘要 A synthetic particulate vector is disclosed and is characterized in that it has selective tropism for a type of cell and that it comprises: a non liquid hydrophilic nucleus, a first layer or crown of a lipid nature linked to the nucleus by covalent bonds, a second layer or external film of phospholipids linked to the firs layer by hydrophobic interactions, B apolipoprotein molecules attached to the phospholipid layer. A method of preparing said vector and a pharmaceutical composition containing it are also disclosed.
申请公布号 FR2677272(A1) 申请公布日期 1992.12.11
申请号 FR19910006812 申请日期 1991.06.05
申请人 A S BIOVECTEURS;REGAUD CENTRE CLAUDIUS 发明人 SAMAIN DANIEL;FAVRE GILLES;NGUYEN FREDERIQUE;PEYROT MARIANNE;MERCIER PHILIPPE;DE MIGUEL IGNACIO;MENIALI JAOUAD
分类号 A61K9/50;A61K9/127;A61K9/16;A61K9/51;A61K31/65;A61K31/70;A61K45/00;A61K47/42;A61K47/48;A61P35/00;(IPC1-7):B01J13/02;A61K9/62 主分类号 A61K9/50
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