发明名称 |
VECTEUR PARTICULAIRE A TROPISME SELECTIF, PROCEDE DE PREPARATION ET COMPOSITION PHARMACEUTIQUE. |
摘要 |
A synthetic particulate vector is disclosed and is characterized in that it has selective tropism for a type of cell and that it comprises: a non liquid hydrophilic nucleus, a first layer or crown of a lipid nature linked to the nucleus by covalent bonds, a second layer or external film of phospholipids linked to the firs layer by hydrophobic interactions, B apolipoprotein molecules attached to the phospholipid layer. A method of preparing said vector and a pharmaceutical composition containing it are also disclosed.
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申请公布号 |
FR2677272(A1) |
申请公布日期 |
1992.12.11 |
申请号 |
FR19910006812 |
申请日期 |
1991.06.05 |
申请人 |
A S BIOVECTEURS;REGAUD CENTRE CLAUDIUS |
发明人 |
SAMAIN DANIEL;FAVRE GILLES;NGUYEN FREDERIQUE;PEYROT MARIANNE;MERCIER PHILIPPE;DE MIGUEL IGNACIO;MENIALI JAOUAD |
分类号 |
A61K9/50;A61K9/127;A61K9/16;A61K9/51;A61K31/65;A61K31/70;A61K45/00;A61K47/42;A61K47/48;A61P35/00;(IPC1-7):B01J13/02;A61K9/62 |
主分类号 |
A61K9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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