| 摘要 |
<p>This invention presents novel assay devices employing a capture reagent, involving a specific binding member attached to a charged substance, and a porous material containing a capture or reaction zone that is oppositely charged with respect to the capture reagent. In one embodiment, a test sample suspected of containing the analyte of interest is contacted with the capture reagent to form a charged capture reagent/analyte complex. The complex is then contacted to the oppositely charged capture or reaction zone to attract, attach, and immobilize the capture reagent/analyte complex. With an appropriate indicator reagent, both sandwich and competitive assays can be performed.</p> |
