发明名称 |
IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS |
摘要 |
2110590 9221382 PCTABS00017 Ultrasound contrast agents in the form of microparticles comprising a biotolerable matrix (e.g. of a carbohydrate or an X-ray contrast agent) in association with a gas or a precursor therefor are stabilised to enhance their in vivo stability and/or echogenicity by covalently modifying the structure of the matrix, e.g. to introduce crosslinking groups or to attach lipophilic groups and/or molecules. The covalent moieties may include biodegradable linkages to assist rapid subsequent elimination of the contrast agents from the system.
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申请公布号 |
CA2110590(A1) |
申请公布日期 |
1992.12.10 |
申请号 |
CA19922110590 |
申请日期 |
1992.06.03 |
申请人 |
NYCOMED IMAGING AS |
发明人 |
KLAVENESS, JO;RONGVED, PAL;STRANDE, PER;RONGVED P L;STRANDE PER |
分类号 |
A61K47/48;A61K49/00;A61K49/04;A61K49/22;(IPC1-7):A61K49/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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