发明名称 |
Process and intermediates for the preparation of spiro[isoquinoline-4(1H),3-pyrrolidine]1,2,3,5 (2H)-tetrones which are useful as aldose reductase inhibitors |
摘要 |
This invention relates to a process for producing spiro-isoquinolinepyrrolidines. The compounds have pharmaceutical properties which render them beneficial for the prevention or treatment of diabetes mellitus associated complications.
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申请公布号 |
US5169948(A) |
申请公布日期 |
1992.12.08 |
申请号 |
US19920816198 |
申请日期 |
1992.01.02 |
申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
MALAMAS, MICHAEL S. |
分类号 |
C07C69/76;C07D217/26;C07D471/10 |
主分类号 |
C07C69/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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