FIBRONECTIN RECEPTOR

摘要

The present invention provides a substantially pure integrin-type receptor characterized in that it consists of an alpha v and a beta 1 subunit. The alpha v beta 1 integrin binds to fibronectin and GRGDSPK but does not bind to vitronectin. The alpha v beta 1 integrin can be used to determine the presence of a alpha v beta 1 ligand and to develop adhesion peptides specific for the various integrins. The presence of the alpha v beta 1 integrin can be used to assess ability of cells to adhere to fibronectin.