BUCCALE VERABREICHUNG VON OESTROGENEN.

摘要

An adequate blood plasma level of 17-beta-estradiol or ethinyl estradiol is attained in a patient in need of estrogen therapy by administration of a dose of 17-beta-estradiol or ethinyl estradiol or a pharmaceutically acceptable ester thereof not greater than 150 micrograms into the vestibule of the buccal cavity of the patient and maintaining the dose in contact with the oral mucosa for a period of time sufficient for transmucosal absorption of a sufficient amount of estrogen to produce a therapeutically effective plasma concentration of estrogen.