发明名称 |
Use of phosphatidyl serine derivs. - for treatment of depression and loss of cerebral function e.g. Parkinson's disease and Alzheimer's disease |
摘要 |
Use of 1,2-substd. phosphatidyl serine derivs. of formula (I) or a salt of (I), in prepn. of a medicament for therapy of disorders leading to depression and/or disorders or cerebral functions, esp. redn. or loss of memory, is new. In (I) R1, R2 = satd. or unsatd. 8-24C hydrocarbyl residue. USE/ADVANTAGE - (I) are useful in treatment of diseases such as Parkinson's disease, Alzheimer's disease, organic brain syndrome, AIDS dementia, depressive pseudo-dementia, dementia(l) syndromes, deliria, intoxications, withdrawal syndromes or cytopathic influences. Dosage is 1-20 mg/kg/day administered, e.g. as tablets or by injection. Some phosphatidyl serine derivs. are known for treatment of tumours and CNS disorders.
|
申请公布号 |
DE4117629(A1) |
申请公布日期 |
1992.12.03 |
申请号 |
DE19914117629 |
申请日期 |
1991.05.29 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN EV, 3400 GOETTINGEN, DE |
发明人 |
EIBL, HANSJOERG, PROF. DR., 3406 BOVENDEN, DE;BORMANN, JOACHIM, DR., 3400 GOETTINGEN, DE;SCHATTON, WOLFGANG, DR., 6236 ESCHBORN, DE |
分类号 |
C07F9/10 |
主分类号 |
C07F9/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|