摘要 |
Vitronectin, an adhesion protein, acts as a growth inhibitory modulator of vascular smooth muscle cell proliferation, a phenomenon which is known to cause atherosclerosis. The invention provides a method of inhibiting smooth muscle cell proliferation comprising administration of vitronectin, as well as vitronectin for such use and pharmaceutical compositions containing vitronectin. Preferably, the vitronectin is the extended form thereof. |