| 摘要 |
<p>A new therapeutic use of phospholipid derivatives as immunosuppressants is described, these phospholipid derivatives having a general formula (I): <CHEM> wherein A = H; -(CH2)nOH, -(CH2)n-O-CO-R (with n= 1, 2); B = <CHEM> -(CH2)m-O-CO-R (with m= 1,2,3,4) with the limitation that when A = -(CH2)n-O-CO-R, m = 1,2; and Y = serine or inositol, and wherein the R groups may be the same or different, and are radicals of acids that are aliphatic, aromatic, arylaliphatic, alicyclic, or heterocyclic on the condition that at least one R group is the radical of a monounsaturated or polyunsaturated fatty acid, and is preferably chosen from the group consisting of palmitoleic acid, oleic acid, linoleic acid, linolenic acid, and arachidonic acid.</p> |
