发明名称 |
Intermediates for the synthesis of 19-nor vitamin D compounds. |
摘要 |
<p>New intermediate compounds that can be used effectively for the synthesis of a broad range of 1 alpha -hydroxy-19-nor-vitamin D compounds. These novel intermediates are characterized by a group selected from hydroxy methyl (-CH2OH), carboxaldehyde (-CHO), and carboxy ester (-COOAlkyl) at the carbon 22 position of the side chain of a 19-nor-vitamin D nucleus. Intermediates of this type are useful for the introduction of side chain units and thus represent important synthons for the preparation of many different 19-nor-vitamin D compounds.</p> |
申请公布号 |
EP0516411(A1) |
申请公布日期 |
1992.12.02 |
申请号 |
EP19920304838 |
申请日期 |
1992.05.28 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
DELUCA, HECTOR FLOYD;SCHNOES, HEINRICH KONSTANTINE;PERLMAN, KATO LEONARD |
分类号 |
C07C47/267;C07C401/00;C07C47/277;C07F7/18 |
主分类号 |
C07C47/267 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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