| 发明名称 |
INHIBITOR OF DENATURED LDL FORMATION. |
| 摘要 |
<p>A pharmaceutical composition containing as the active ingredient a compound which presents low-density lipoproteins (LDL) represented by the compounds of formula (I) from being negatively charged. This composition inhibits the LDL from undergoing denaturation (oxidation) necessary for the recognition by a scavenger acceptor, and is used for treating arteriosclerosis, peptic ulcer, cancer, ischemic organ disease, inflammation and pulmonary silicosis. <CHEM></p> |
| 申请公布号 |
EP0515684(A1) |
申请公布日期 |
1992.12.02 |
| 申请号 |
EP19910904623 |
申请日期 |
1991.02.14 |
| 申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
KATO, YASUYUKI;TAMURA, KUNIO;OHBA, YASUHIRO;KAWABE, YOSHIKI;SHINSHI, OSAMU |
| 分类号 |
A61K31/10;A61K31/135;A61K31/165;A61K31/17;A61K31/19;A61K31/195;A61K31/215;A61K31/22;A61K31/275;A61K31/335;A61K31/34;A61K31/35;A61K31/36;A61K31/38;A61K31/40;A61K31/415;A61K31/44;A61K31/47;A61K31/495;A61K31/535;C07C215/50;C07C215/74;C07C215/76;C07C217/84;C07C229/18;C07C229/38;C07C229/60;C07C233/25;C07C233/29;C07C233/43;C07C233/75;C07C235/50;C07C235/56;C07C271/28;C07C275/34;C07C279/28;C07C309/73;C07C311/21;C07C323/20;C07C323/32;C07C323/36;C07C323/60;C07C335/18;C07D207/32;C07D207/335;C07D213/38;C07D213/75;C07D213/82;C07D215/20;C07D215/22;C07D215/233;C07D233/54;C07D235/06;C07D261/20;C07D295/192;C07D307/52;C07D311/32;C07D311/58;C07D317/58;C07D317/66;C07D333/20;C07D521/00;C07F7/18 |
主分类号 |
A61K31/10 |
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