发明名称 |
CHELATES,THEIR METAL COMPLEXES AS WELL AS THEIR USE IN DIAGNOSIS AND TREATMENT |
摘要 |
The invention relates to compounds of the general formula I <IMAGE> in which A comprises a functional group which is suitable for coupling to compounds which undergo selective accumulation, and R<1>, R<2>, R<3>, R<4> and R<5> may have a variety of meanings. B is a group which is suitable for the coordinative bonding of metal ions. The compounds are used for the complexation of radioactive metal ions, especially rhenium and technetium isotopes, and are used in medical diagnosis and therapy. |
申请公布号 |
ZA9201717(B) |
申请公布日期 |
1992.11.25 |
申请号 |
ZA19920001717 |
申请日期 |
1992.03.06 |
申请人 |
INSTITUT FUER DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAET BERLIN |
发明人 |
REINHARD NEUMEIER;WOLFGANG KRAMP;HELMUT R. MAECKE;GERHARD ROHLFS |
分类号 |
A61K31/13;A61K31/195;A61K31/22;A61K31/44;A61K31/4418;A61K49/00;A61K51/04;A61K51/10;A61P35/00;C07B59/00;C07C251/24;C07C251/40;C07C309/49;C07C323/32;C07C331/28;C07D213/64;C07D213/70;C07D213/73;C07D495/04;C07F1/08;C07F13/00;C07J41/00 |
主分类号 |
A61K31/13 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|