| 发明名称 |
LIVE VACCINES |
| 摘要 |
Attenuated microorganism for use in immunoprophylaxis in which the attenuation is brought about by the presence of a mutation in the DNA sequence of the microorganism which encodes, or which regulates the expression of DNA encoding a protein that is produced in response to environmental stress, the microorganism optionally being capable of expressing DNA encoding a heterologous antigen. |
| 申请公布号 |
ZA9102397(B) |
申请公布日期 |
1992.11.25 |
| 申请号 |
ZA19910002397 |
申请日期 |
1991.03.28 |
| 申请人 |
THE WELLCOME FOUNDATION LIMITED |
发明人 |
STEVEN NEVILLE CHATFIELD;GORDON DOUGAN;IAN GEORGE CHARLES;CARLOS ESTENIO HORMAECHE;KEVIN STUART JOHNSON |
| 分类号 |
A61K39/02;A61K39/112;A61P31/04;C07K14/255;C12N1/21;C12N9/52;C12N15/00;C12N15/09;C12R1/01;C12R1/42 |
主分类号 |
A61K39/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
