| 发明名称 |
Use of phosphonomethylphosphinate squalene synthetase inhibitors for the manufacture of a medicament for the lowering cholesterol. |
| 摘要 |
<p>A method is provided for inhibiting cholesterol biosynthesis by inhibiting de novo squalene production employing methylene phosphbnoalkylphosphinate compounds.</p> |
| 申请公布号 |
EP0514124(A2) |
申请公布日期 |
1992.11.19 |
| 申请号 |
EP19920304252 |
申请日期 |
1992.05.12 |
| 申请人 |
E.R. SQUIBB & SONS, INC. |
发明人 |
BILLER, SCOTT A.;MAGNIN, DAVID R. |
| 分类号 |
A61K31/66;A61K31/665;A61K31/67;A61K31/675;A61P3/06;A61P9/10;C07F9/38;C07F9/40 |
主分类号 |
A61K31/66 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
