发明名称 |
Novel polypeptides with affinity to lipopolysaccharides and their uses. |
摘要 |
<p>A novel polypeptide sequence having the formula <IMAGE> in which A1 is a hydrogen or at least one and no more than two amino acids selected from the group consisting of lysine and arginine, A2 is a tyrosine, phenylalanine or tryptophan residue, A3 is an arginine or lysine residue, A4 is at least one and no more than two amino acids selected from the group consisting of lysine and arginine, and A5 is an -OH or an NH2, is described. The polypeptide may be used in a pharmaceutical composition as an antimicrobial or antiviral agent, specifically as an anti-HIV agent. <IMAGE></p> |
申请公布号 |
EP0513613(A1) |
申请公布日期 |
1992.11.19 |
申请号 |
EP19920107509 |
申请日期 |
1992.05.04 |
申请人 |
SEIKAGAKU KOGYO KABUSHIKI KAISHA |
发明人 |
FUJII, NOBUTAKA;YAMAMOTO, NAOKI;MATSUMOTO, AKIYOSHI;WAKI, MICHINORI |
分类号 |
C07K14/00;A61K38/00;A61K38/10;A61K38/12;C07K7/08;C07K14/435 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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