发明名称 |
STABILIZATION OF THE ENZYME URATE OXIDASE IN LIQUID FORM |
摘要 |
This invention relates to a process for stabilizing the enzyme urate oxidase (commonly known as uricase) in liquid form, and to the relative compositions which can then be obtained, with particular reference to compositions containing a Trinder reagent. According to the process of the invention, uricase can be stabilized in liquid form by adding to the composition containing the enzyme a substituted or unsubstituted dicarboxylic acid containing from 2 to i carbon atoms, and preferably 4 or 5. Aspartic acid has shown to be particularly effective in providing said stabilizing activity in liquid uricase compositions containing a Trinder reagent.
|
申请公布号 |
CA2068496(A1) |
申请公布日期 |
1992.11.18 |
申请号 |
CA19922068496 |
申请日期 |
1992.05.12 |
申请人 |
INSTRUMENTATION LABORATORY S.R.L. |
发明人 |
D'ALTERIO, MAURIZIO;FRONTINI, DARIO;PAPAGNI, MAURO |
分类号 |
C12N9/06;C12N9/96;C12Q1/26;C12Q1/62;(IPC1-7):C12N9/06;C12Q1/28 |
主分类号 |
C12N9/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|