发明名称 |
ASSAY METHODS INVOLVING OUABAIN |
摘要 |
Methods for diagnosing pre-hypertension, hypertension, congestive cardiomyopathy, renal failure, salt-sensitivity and adenomas and endocrine cell hyperplasias are disclosed. Also disclosed are methods for monitoring hypertension therapy, congestive cardiomyopathy therapy, renal failure therapy and adenoma and endocrine call hyperplasia therapy. These methods involve using an antibody having binding specificity to ouabain to immunologically measure the level of human ouabain in body fluid or tissue of a subject. Additionally, methods for treating a hypertensive subject by inducing passive or active immunity to human ouabain in the subject are disclosed, along with an antibody having binding specificity for ouabain.
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申请公布号 |
US5164296(A) |
申请公布日期 |
1992.11.17 |
申请号 |
US19900575714 |
申请日期 |
1990.08.31 |
申请人 |
UNIVERSITY OF MARYLAND AT BALTIMORE |
发明人 |
BLAUSTEIN, MORDECAI P.;HAMLYN, JOHN M.;HARRIS, DOUGLAS W.;LUDENS, JAMES H.;MATHEWS, WILLIAM R.;FISHER, JED F.;MANDEL, FREDERIC;DUCHARME, DONALD W. |
分类号 |
A61K39/395;A61P9/12;C07J17/00;C07K14/00;C07K14/76;C07K16/00;C07K16/18;C07K16/44;G01N33/53 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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