发明名称 |
PREPARATION AND USE OF SOLID BEADS HAVING CONTROLLED CHARACTERISTICS |
摘要 |
Processes for preparing and using controlled characteristic beads are disclosed, the process of making the beads including the steps combining at least one monoethylenically unsaturated monomer with a polyethylenically unsaturated monomer and a monomer-soluble initiator to form a monomer phase; combining the monomer phase with a liquid in which the monomer phase is substantially immiscible to form a reaction mixture such that when the monomer phase is vinyl in nature the liquid also includes a high molecular weight, high charge density surfactant, and when the monomer phase is acrylic in nature the liquid includes an organic polymer colloid suspending agent; agitating the reaction mixture at an initial speed and temperature for a time sufficient to homogenize the reaction mixture, thereby producing first intermediate droplets, and subsequently reducing the agitation speed to a level sufficient to allow limited coalescence of the first intermediate droplets to form second intermediate droplets having size distribution with less than about 30 % variance from the mean; and polymerizing the second intermediate droplets to form solid, substantially non-porous beads. One method of using controlled characteristic beads includes combining the beads produced by the process with a sample containing two separable components and centrifuging the sample for a time and at a rate sufficient to produce distinct bands of components. |
申请公布号 |
AU1871292(A) |
申请公布日期 |
1992.11.17 |
申请号 |
AU19920018712 |
申请日期 |
1992.04.20 |
申请人 |
ADVANCED POLYMER SYSTEMS, INC. |
发明人 |
CHRISTINE J. Y LIAU;KEMON JOHN PAPACOSTA;CONSTANTIN MAZAS;ROBERT P EURY;SERGIO NACHT |
分类号 |
A61M1/36;C08F2/00;C08F2/22;G01N33/50 |
主分类号 |
A61M1/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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