Novel synthetic atrial peptides are provided with enhanced natriuretic properties by substituting one or two arginine residues for the N-terminal ser-ser in atriopeptins I, II and III and their physiologically acceptable salts, esters and amides.
申请公布号
DE3782073(D1)
申请公布日期
1992.11.12
申请号
DE19873782073
申请日期
1987.03.26
申请人
MONSANTO CO., ST. LOUIS, MO., US
发明人
TJOENG, FOE SIONG, MANCHESTER MISSOURI 63021, US;FOK, KAM FOOK, ST. LOUIS MISSOURI 63146, US;ADAMS, PAUL STEVEN, ST. CHARLES MISSOURI 63303, US