发明名称 New 13-carboxy-sterol cpd. ergokonin C - useful as antibiotic and antifungal agent, and as intermediate for steroid synthesis
摘要 Novel antifungal antibiotic, ergokonin C has the chemical name C-13-carboxy-3-O(2'-amino-2'-methylpropionylcarboxy) steriol and is of formula (I). USE/ADVANTAGE - (I) is an ergokonin-type antifungal and antibiotic cpd. In tests (I) has a minimal growth inhibiting effect of 0.3, 0.05 and 10 microg (I)/diffusion zone for candida befir, Kluyveromyces marxianus and Bacillus subtilis respectively. (I) are also intermediate in the prepn. of steroid cpds.
申请公布号 DE4115490(A1) 申请公布日期 1992.11.12
申请号 DE19914115490 申请日期 1991.05.11
申请人 ARZNEIMITTELWERK DRESDEN GMBH, O-8122 RADEBEUL, DE 发明人 SCHLEGEL, BRIGITTE, DR.RER.NAT., O-6920 JENA, DE;GRAEFE, UDO, PROF. DR.SC.NAT.;IHN, WOLFGANG, DR.RER.NAT., O-6900 JENA, DE;BORMANN, ERNST-JOACHIM, DR.SC.NAT., O-6902 JENA, DE;RUDAT, WOLF-RUEDIGER, DR.RER.NAT., O-8054 DRESDEN, DE;HEIDENBLUTH, KARL-HEINZ, DR.RER.NAT., O-8122 RADEBEUL, DE
分类号 C07D303/17;C07J71/00 主分类号 C07D303/17
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