发明名称 |
NEW 2-PIPERAZINYLBENZIMIDAZOLE DERIVATIVES |
摘要 |
A PROCESS FOR PREPARING NEW 2-PIPERAZINYLBENZIMIDAZOLE DERIVATIVES A description is made of the preparation of new 2piperazinylbenzimidazole derivatives, of general formula where R can be a hydrogen atom, a short chain alkyl group and a phenyl radical, substituted in position four by a halogen, and R1 can be a hydrogen atom; an alkoxycarbonyl radical, a hydroxymethyl group and a diphenylmethyl group, and their addition salts with pharmaceutically acceptable acids. These compounds are pharmacologically active as antagonists of the serotonin 5HT3 receptors.
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申请公布号 |
CA2068292(A1) |
申请公布日期 |
1992.11.11 |
申请号 |
CA19922068292 |
申请日期 |
1992.05.08 |
申请人 |
FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS S.A.(FAES) |
发明人 |
ORJALES-VENERO, AURELIO;GARCIA-DOMINGUEZ, NEFTALI;RUBIO-ROYO, VICTOR;RODES-SOLANES, ROSA |
分类号 |
A61K31/495;A61K31/496;A61P1/08;A61P25/04;A61P25/06;A61P25/20;A61P43/00;C07D235/30;(IPC1-7):C07D403/04 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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