发明名称 NEW 2-PIPERAZINYLBENZIMIDAZOLE DERIVATIVES
摘要 A PROCESS FOR PREPARING NEW 2-PIPERAZINYLBENZIMIDAZOLE DERIVATIVES A description is made of the preparation of new 2piperazinylbenzimidazole derivatives, of general formula where R can be a hydrogen atom, a short chain alkyl group and a phenyl radical, substituted in position four by a halogen, and R1 can be a hydrogen atom; an alkoxycarbonyl radical, a hydroxymethyl group and a diphenylmethyl group, and their addition salts with pharmaceutically acceptable acids. These compounds are pharmacologically active as antagonists of the serotonin 5HT3 receptors.
申请公布号 CA2068292(A1) 申请公布日期 1992.11.11
申请号 CA19922068292 申请日期 1992.05.08
申请人 FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS S.A.(FAES) 发明人 ORJALES-VENERO, AURELIO;GARCIA-DOMINGUEZ, NEFTALI;RUBIO-ROYO, VICTOR;RODES-SOLANES, ROSA
分类号 A61K31/495;A61K31/496;A61P1/08;A61P25/04;A61P25/06;A61P25/20;A61P43/00;C07D235/30;(IPC1-7):C07D403/04 主分类号 A61K31/495
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