发明名称 BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE
摘要 2102780 9220642 PCTABS00017 This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.
申请公布号 CA2102780(A1) 申请公布日期 1992.11.11
申请号 CA19922102780 申请日期 1992.05.06
申请人 RHONE POULENC RORER INT 发明人 SPADA ALFRED P;MAGUIRE MARTIN P;PERSONS PAUL E;MYERS MICHAEL R
分类号 A61K31/085;A61K31/047;A61K31/40;A61K31/403;A61K31/404;A61K31/425;A61K31/428;A61K31/435;A61K31/4375;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4412;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4433;A61K31/47;A61K31/4709;A61K31/472;A61K31/4725;A61K31/495;A61K31/498;A61K31/505;A61K31/517;A61K31/535;A61K31/536;A61P9/10;A61P33/00;A61P35/00;A61P35/02;C07C43/205;C07C43/225;C07C43/23;C07D209/04;C07D213/30;C07D213/64;C07D215/14;C07D215/18;C07D215/20;C07D215/22;C07D215/233;C07D215/38;C07D215/50;C07D217/24;C07D239/74;C07D239/88;C07D239/91;C07D239/93;C07D239/94;C07D241/42;C07D241/52;C07D265/22;C07D277/64;C07D401/04;C07D401/06;C07D401/12;C07D403/04;C07D403/06;C07D403/12;C07D405/04;C07D405/12;C07D409/04;C07D409/06;C07D409/12;C07D417/04;C07D471/04;C07D521/00;C12N9/99;(IPC1-7):C07D215/20;A61K31/33 主分类号 A61K31/085
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