发明名称 |
BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE |
摘要 |
2102780 9220642 PCTABS00017 This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.
|
申请公布号 |
CA2102780(A1) |
申请公布日期 |
1992.11.11 |
申请号 |
CA19922102780 |
申请日期 |
1992.05.06 |
申请人 |
RHONE POULENC RORER INT |
发明人 |
SPADA ALFRED P;MAGUIRE MARTIN P;PERSONS PAUL E;MYERS MICHAEL R |
分类号 |
A61K31/085;A61K31/047;A61K31/40;A61K31/403;A61K31/404;A61K31/425;A61K31/428;A61K31/435;A61K31/4375;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4412;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4433;A61K31/47;A61K31/4709;A61K31/472;A61K31/4725;A61K31/495;A61K31/498;A61K31/505;A61K31/517;A61K31/535;A61K31/536;A61P9/10;A61P33/00;A61P35/00;A61P35/02;C07C43/205;C07C43/225;C07C43/23;C07D209/04;C07D213/30;C07D213/64;C07D215/14;C07D215/18;C07D215/20;C07D215/22;C07D215/233;C07D215/38;C07D215/50;C07D217/24;C07D239/74;C07D239/88;C07D239/91;C07D239/93;C07D239/94;C07D241/42;C07D241/52;C07D265/22;C07D277/64;C07D401/04;C07D401/06;C07D401/12;C07D403/04;C07D403/06;C07D403/12;C07D405/04;C07D405/12;C07D409/04;C07D409/06;C07D409/12;C07D417/04;C07D471/04;C07D521/00;C12N9/99;(IPC1-7):C07D215/20;A61K31/33 |
主分类号 |
A61K31/085 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|