发明名称 ANTIHYPERLIPOPROTEINEMIC 5-BENZYL SUBSTITUTED-BENZIMIDAZOLINE-2-THION DERIVATIVES
摘要 Novel antihyperlipoproteinemic compounds are disclosed of the formula I, <IMAGE> (I) wherein X is a halogen atom, methyl, ethyl, methoxy or ethoxy group, Y is hydroxy if X is methoxy or ethoxy, otherwise it is a hydrogen atom or a, methoxy or ethoxy group, Z is a methoxy or ethoxy group if X or Y is a methoxy group or an ethoxy group; otherwise it is hydrogen atom, The invention also covers antiartheriosclerotic, antihyperlipoproteinemic pharmaceutical compositions, suitable for inhibiting the formation of thrombuses, comprising the compounds of formula I in an effective dose, a process for preparing the same and methods for the treatment of hyperlipoproteinemia with the aid of the said compounds or compositions.
申请公布号 US5162359(A) 申请公布日期 1992.11.10
申请号 US19910753751 申请日期 1991.09.03
申请人 RICHTER GEDEON VEGYESZETI GYAR RT. 发明人 HARSANYI, KALMAN;TETENYI, PETER;NAGY, TAMAS;CSEHI, ATTILA;GIZUR, TIBOR;HEGEDUES, BELA;MADERSPACH, ANDREA;JAVOR, ANDRAS;HAJOS, GYOERGY;SZPORNY, LASZLO
分类号 A61K31/425;A61K31/4184;A61P3/06;A61P7/02;A61P9/10;C07D235/28 主分类号 A61K31/425
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