| 摘要 |
PURPOSE:To obtain a new chain terpene useful as an intermediate for inexpensively producing and supplying a large amount of sarcophytol A having anti- carcinogenic promoter action and antitumor action. CONSTITUTION:A chain terpene shown by the formula [X is Cl, OC(O)R<1> (R<1> is H, 1-4C alkyl or phenyl which may contain substituent group), SR<2>, S(O)R<2> (R<2> is 1-4C alkyl or phenyl which may contain substituent group), NR<3>R<4> or N(O)R<3>R<4> (R<3> and R<4> are 1-4C alkyl or R<3> and R<4> are bonded to from ring); R is cyano, formyl or C(O)OR<5> (R<5> is 1-4C alkyl); n is 0 or 1 with the proviso that X is Cl or OC(O)R<1> when n=0]. The compound shown by formula, for example, is obtained by reacting geranial with Wittig-Horner reagent in the presence of a base. |
