| 摘要 |
PURPOSE: To produce high-purity, free-flowing and directly compressible vitamin B1 , vitamin B2 , vitamin B6 , vitamin C, sodium ascorbate or calcium ascorbate without adding a lubricant thereto. CONSTITUTION: A 5-25%, preferably a 5-12% aqueous solution or suspension of vitamin B1 , vitamin B2 , vitamin B6 , vitamin C, sodium ascorbate or calcium ascorbate is preferably sprayed in a drying tower and hot air at 120-200 deg.C is preferably simultaneously introduced into the drying tower to carry out the spray-drying. Thereby, the free-flowing, directly compressible and purest possible corresponding vitamin or its salt of preferably 99.7-100% purity readily convertible into a tablet or other solid administration forms, preferably vitamin C, thiamine hydrochloride, riboflavin nitrate, riboflavin sodium phosphate, pyridoxine hydrochloride or pyridoxal phosphate is obtained.
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