发明名称 |
BIODEGRADABLE MICROSPHERES AS A CARRIER FOR MACROMOLECULES |
摘要 |
A method for preparing biodegradable microspheres having a three-dimensional network in which biologically active macromolecular agents are physically entrapped therein. The microsphere is able to release the macromolecular agent at a controlled rate. The method involves emulsifying a vinyl derivative of a biodegradable hydrophilic polymer, a water-soluble monovinyl monomer and a biologically active macromolecule in water, and copolymerizing the biodegradable hydrophilic polymer and the water-soluble monovinyl monomer such that the biologically active macromolecule is entrapped therein. |
申请公布号 |
CA1309657(C) |
申请公布日期 |
1992.11.03 |
申请号 |
CA19870537378 |
申请日期 |
1987.05.19 |
申请人 |
DELUCA, PATRICK P. |
发明人 |
DELUCA, PATRICK P.;RYPACEK, FRANTISEK |
分类号 |
A61K47/34;A61K9/16;A61K9/26;A61K9/52;A61K47/32;A61K47/36;A61K47/42;B01J13/14;C08F2/22;C08F2/44 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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