| 摘要 |
<p>A novel tricyclic triazole derivative represented by general formula (I) and a pharmacologically acceptable salt thereof, useful as an antiinflammatory, antiallergic and anti-PAF drug, and a process for the production thereof. In formula (I), R1 represents hydrogen, lower alkyl or C¿3? to C5 cycloalkyl; R?2 and R3¿ represent each hydrogen, lower alkyl, lower alkoxy or halogen; W represents C=O or CR4R5 wherein R?4 and R5¿ represent each hydrogen or lower alkyl; A represents C¿1? to C5 saturated or unsaturated alkylene which may contain a heteroatom; l represents 0 to 2; n represents 1 to 3; symbol -- represents a single or double bond; Y represents N or C; and Z represents C(B)Ar?1Ar2¿ (wherein B represents hydrogen, hydroxy or methoxy, and Ar?1 and Ar2¿ represent each hydrogen or (un)substituted aryl), CAr1Ar2 (wherein Ar?1 and Ar2¿ are each as defined above), O-CHAr1Ar2 (wherein Ar?1 and Ar2¿ are each as defined above) or a condensed aromatic ring.</p> |
