| 摘要 |
PURPOSE:To obtain an aqueous solution of silk fibroin useful for cosmetic base, etc., excellent in storage stability, film-forming performances, etc., by blending an aqueous solution of silk fibroin with (meth)acrylic acid (derivative) with a radical polymerization catalyst and subjecting to graft polymerization. CONSTITUTION:(A) Sericin is removed from a silk fibroin raw material (e.g. raw silk waste or silk cloth waste) optionally in the presence of an activator in warm water or in the presence of an enzyme in warm water and the silk fibroin raw material is dried. (B) The silk raw material obtained in the process A is dissolved in a solvent (preferably aqueous solution of hydrochloride or nitrate of Ca or Mg) at 60-95 deg.C and then the salt is removed by using a dialyzer using a hollow yarn, etc. (C) The aqueous solution after the treatment is blended with one or more compounds (e.g. methacrylamide or methacrylic acid) selected from (meth)acrylic acid or a derivative thereof and stirred in the presence of a radical polymerization catalyst (e.g. persulfate or hydrogen peroxide) preferably in a nitrogen atmosphere under heating at 40-100 deg.C to produce an aqueous solution of silk fibroin modified with (meth)acrylic acid (derivative). |
