Azole compounds, their production and use.

摘要

An azole compound represented by the formula (I): <CHEM> wherein X is a nitrogen atom or CH; Ar is a substituted phenyl group; R<1> and R<2> independently are a hydrogen atom or a lower alkyl group, or they may combine together to form a lower alkylene group; B is a group of the formula: <CHEM> (wherein R<3> and R<4> independently are a hydrogen atom, an optionally substituted aliphatic or aromatic hydrocarbon residue or an optionally substituted heterocyclic group, or they may form an optionally substituted heterocyclic group together with the nitrogen atom to which they are bonded; and n denotes an integer of 0 to 2), or a group of the formula: <CHEM> (wherein R<5> and R<6> independently are a hydrogen atom, an optionally substituted aliphatic or aromatic hydrocarbon residue group or an optionally substituted heterocyclic group, or they may form an optionally substituted heterocyclic group together with the nitrogen atom and sulfur atom to which they are bonded; and m denotes an integer of 0 to 2); and R<7> is a hydrogen atom or an acylated hydroxyl group, or may form a bond together with R<1>, or a salt thereof, which is useful as an antifungal agent.