发明名称 |
DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE |
摘要 |
2-(Amino or methyl)-6-(methyl or amino)-4- (substituted phenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid esters have a specific class of heterocyclic groups as the alcohol moiety. These compounds have a variety of valuable activities, including antihypertensive and Ca++-blocking activities, leading to their use for the treatment of circulatory and coronary disorders. They may be prepared by condensation of appropriate substituted benzylideneacetoacetic acid esters with appropriate amidinoacetic acid esters.
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申请公布号 |
CA1309098(C) |
申请公布日期 |
1992.10.20 |
申请号 |
CA19870548953 |
申请日期 |
1987.10.09 |
申请人 |
SANKYO COMPANY LIMITED;UBE INDUSTRIES LIMITED |
发明人 |
KOIKE, HIROYUKI;YOSHIMOTO, MASAFUMI;NISHINO, HIROSHI |
分类号 |
A61K31/455;A61K31/4427;A61P3/00;A61P3/14;A61P7/02;A61P9/00;A61P9/08;A61P9/12;C07D205/04;C07D211/80;C07D211/90;C07D401/12;C07D413/14;(IPC1-7):C07D401/12 |
主分类号 |
A61K31/455 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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