发明名称 |
Serine protease inhibitors |
摘要 |
Novel peptides which exhibit inhibitory activity toward serine proteases and methods for preparing and using same are disclosed. In one aspect, the present invention provides peptides comprising a generic inhibitory core having a functional site recognition sequence fused to the N-terminus. The functional site recognition sequence is adapted to provide enhanced selectivity and/or potency for a target protease.
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申请公布号 |
US5157019(A) |
申请公布日期 |
1992.10.20 |
申请号 |
US19910728002 |
申请日期 |
1991.07.01 |
申请人 |
MONSANTO COMPANY |
发明人 |
GLOVER, GEORGE I.;SCHASTEEN, CHARLES S. |
分类号 |
A61K38/00;C07K14/81 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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