发明名称 USE OF STEROID HORMONES IN COMPOSITIONS FOR INDUCING T CELL LYMPHOKINE PRODUCTION
摘要 <p>Disclosed is a method for enhancing the production of T cell lymphokines, which comprises exposing T cell lymphocytes which have a potential to make selected T cell lymphokines to an appropriate concentration of at least one particular steroid hormone prior to cellular activation. Also disclosed are applications of the method for clinically diagnosing abnormal interleukin production, maintaining in vitro tissue cultures of T cells, overcoming certain types of immunosuppression caused by elevated GCS levels, caused by endogenous production or exogenous administration, use as a vaccine adjuvant to selectively direct the vaccine-induced immune response down a protective, rather than a potentially pathologic or non-protective, immunologic pathway, as a treatment for naturally occuring aging-related decreases in immune function, as a treatment for stress or trauma-induced decreases in immune function, and as an agent to facilitate desensitization to agents to which a warm-blooded animal is allergic.</p>
申请公布号 EP0494224(A4) 申请公布日期 1992.10.14
申请号 EP19900914807 申请日期 1990.09.25
申请人 UNIVERSITY OF UTAH 发明人 DAYNES, RAYMOND, A.;ARANEO, BARBARA, A.
分类号 A61K31/565;A61K31/57;A61K31/59;A61K39/02;A61K39/12;A61K39/395;A61K45/06;A61P37/00;C07J5/00;G01N33/68;(IPC1-7):A61K31/57 主分类号 A61K31/565
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