发明名称 |
Proteinaceous lipid-containing particles. |
摘要 |
<p>Proteinaceous, lipid-containing particles can be prepared by co-expressing in a host cell (i) a self-assembling protein moiety in circumstances where the protein assembles to form a core, which then buds off from the host cell, thereby acquiring a lipid envelope derived from the host cell membrane and (ii) a membrane-bound protein moiety, which becomes integrated in the lipid envelope. The particles have a wide variety of uses. They may be used as an antigen presentation system, or they may for example have site-specific targeting ability, fusogenic properties, enzymic activity, cytotoxic activity, diagnostic utility and/or pharmaceutical activity. <IMAGE></p> |
申请公布号 |
EP0508809(A1) |
申请公布日期 |
1992.10.14 |
申请号 |
EP19920303223 |
申请日期 |
1992.04.10 |
申请人 |
BRITISH BIO-TECHNOLOGY LIMITED |
发明人 |
ADAMS, SALLY ELIZABETH;BURNS, NIGEL ROBERT;FRENCH, TIMOTHY JOHN;GEARING, ANDREW JOHN HUBERT;KINGSMAN, ALAN JOHN;KINGSMAN, SUSAN MARY |
分类号 |
A61K38/00;A61K39/00;A61K39/12;A61K39/155;A61K39/205;A61K39/21;A61P31/12;C07K14/00;C07K14/005;C07K14/11;C07K14/145;C07K14/155;C07K14/16;C07K14/195;C07K14/52;C07K14/705;C07K16/00;C07K19/00;C12N5/10;C12N7/04;C12N15/09;C12N15/12;C12N15/41;C12N15/47;C12N15/49;C12N15/87;C12P21/02;G01N33/53;G01N33/569 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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